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Schoch A, Kettenberger H, Mundigl O, Winter G, Engert J, Heinrich J, et al
When a compound average effect is only 2 kilograms over 12 weeks, many individual participants likely saw minimal to no change, while a smaller subset may have responded more strongly, pulling the average up
If you are experiencing persistent fatigue, its important not to self-diagnose
A final alternative to alleviate FcRn-controlled pathological mechanisms could be to alter FcRn in itself, as may be intended with a gene therapy being developed in a collaboration between Beam and Apellis for a one-time dose of gene-editing molecules targeting FcRn [436, 437]
10.3389/fimmu.2024.1310443 93 GhasemiN.RazaviS.NikzadE
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