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(2019).The recent advances in the mathematical modelling of human pluripotent stem cells

Upon binding to estrogen, ER translocates to the nucleus where it binds to DNA regions containing estrogen-responsive elements (ERE) and subsequently regulates the transcription of numerous genes that are crucial for breast tumorigenesis [4]

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References to metabolic activity are limited to nonclinical research context only

42 , W320W324 (2014)

What the Data Shows The honest answer, based on the published evidence, is mixed rather than negative