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10.1016/j.mrfmmm.2011.11.003 40 FengY.WangS.ChenR.TongX.WuZ.MoX

According to a study, puerarin injections were useful in treating DPN and increased patients overall effectiveness rate and nerve conduction velocity (Wu et al

genetic associations with other risk factors were obtained from summary statistics in the Neale Lab GWAS of the UK Biobank, controlling for age, age 2 , and 20 principal components (Additional file 1: Table S1)

Glutathione supplements, particularly advanced formulations, can be expensive

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Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity