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Oral GLP-1 analogue: perspectives and impact on atherosclerosis in type 2 diabetic patients
More common with compounded formulations than with brand-name pens, possibly due to differences in solution pH, concentration, or inactive ingredients
As insulin levels decrease, the livers expression of key enzymes involved in fat synthesis, such as fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC), is suppressed, reducing fat generation (38)
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Protein intake in adults should not fall below 0.40.5 g/kg/day to avoid muscle atrophy and functional impairments, whereas prolonged intake at or above 2 g/kg/day should be avoided due to potential adverse health effects [42]
Obes Rev , 2021
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