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Certain bacterial species and their metabolic products, particularly short-chain fatty acids like butyrate and propionate, may stimulate L-cell secretion

Fluid balance effects : Spironolactone helps remove excess fluid, while Mounjaros digestive side effects, like vomiting or diarrhoea, can sometimes lead to dehydration

Smith SA, Ogawa SA, Chau L, Whelan KA, Hamilton KE, Chen J, et al

In June 2026 the MHRA approved the Wegovy pill (oral semaglutide 25 mg), the first oral GLP-1 medicine licensed in the UK specifically for weight management

More research is needed into the effects of individual nutrients, specific foods, and dietary patterns in humans

Oral semaglutide has different absorption characteristics compared to injectable forms, which can affect the onset of action