Subramanian, A
Ozempic side effect: Male users reveal change to their genitals after injection Ozempic, the diabetes medication that has soared in popularity for its weight-loss effects, is now at the centre of a new side effect: claims of penis enlargement
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These effects have been observed in NASH, LPS-induced inflammation, and atherosclerosis mouse models (Rakipovski et al., 2018)
Other GLP-1 options include liraglutide (Saxenda) and oral semaglutide (Rybelsus), though both are generally considered less effective for weight loss than injectable semaglutide at higher doses
In the event DSIP does ultimately undergo clinical development, intranasal administration can ensure a higher degree of patient compliance by eliminating side effects and discomfort commonly associated with peptide injections