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The primary mechanism of action involves: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood sugar levels without causing hypoglycaemia when glucose levels are normal [3] [4] Suppressing glucagon release , thereby reducing glucose production by the liver Slowing gastric emptying , which prolongs the feeling of fullness after meals Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger and food intake When administered as medication, GLP-1 receptor agonists mimic these natural effects but with enhanced duration and potency

Enomoto M., Naoe S., Harada M., Miyata K., Saito M., Noguchi Y

NeuroReport 7:18331836 Raps SP, Lai JC, Hertz L, Cooper AJ (1989) Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

The Placebo Effect and Psychological Factors Some reported benefits might stem from the placebo effect, where the belief in the treatment's efficacy leads to perceived improvements

Comprender la base biolgica de esta variabilidad es fundamental para mejorar la seleccin del tratamiento y el asesoramiento al paciente

This article does not promote or guarantee use of semaglutide, tirzepatide, or any specific treatment