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Rationale and design of the Aldose Reductase Inhibition for Stabilization of Exercise Capacity in Heart Failure Trial (ARISE-HF) in patients with high-risk diabetic cardiomyopathy

Research suggests you need to take more than 1 gram per day for more than 8 weeks.) That said, problems with the limited research means that we dont know how effective it really is

Rotation of injection sites: change the site of administration (alternately deltoid, quadriceps femoris, gluteus) to reduce irritation and local reactions

Given the lack of safety data, most clinicians recommend considering alternative weight management approaches during lactation

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95% CI, 0.510.60