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Although GLP-1RAs are known to have action in the brain, it is possible one mechanism by which GLP-1RAs reduce consumption of ingested drugs such as alcohol is, at least in part, through peripheral mechanisms

Both are widely available through peptide suppliers as "research chemicals." Van et al

Active or unstable major depressive disorder (MDD) or other severe psychiatric illnesses (e.g., schizophrenia, bipolar disorder) within the past two years

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Previous rodent studies demonstrated that GLP-1 receptor agonists suppressed the rewarding effects of alcohol and reduced alcohol consumption

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