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It is characterized by mitochondrial contraction, increased mitochondrial membrane density, and a reduction or loss of mitochondrial cristae
Gastrointestinal: Mild transient diarrhea
Unexplained elevated B12 levels warrant medical investigation including liver function tests, renal function assessment, and full blood count
Chronic pharmacological potentiation of this pathway could theoretically promote tumor development or progression in individuals with pre-existing pre-malignant cells
This is the most common and most benign cause of elevated B12
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