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Pharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease

Hemolytic anemia may be more prevalent in patients with both MTHFR and B12 deficiency

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Note that sex differences in pain sensitivity are well established [32] with females generally displaying greater sensitivity [33, 34], and this is in turn influenced by species strains