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See a doctor if your pain isnt improving after a few weeks, is getting worse, or is disrupting your daily life

This controlled and consistent drug delivery also helps reduce systemic side effects by eliminating peak concentrations on bolus (injection) administration

While timing alone is unlikely to be the sole cause, it is one piece of the optimization puzzle that is easy to adjust and test

Children or their care givers were asked to rate the intensity of each individual symptom on a validated 5-point Likert scale (0 indicates no problem, 1 indicates mild problem, 2 indicates moderate problem, 3 indicates severe problem and 4 indicates very severe problem)

These reports are valuable for generating hypotheses but cannot substitute for controlled trials

By three months, their blood sugar levels tend to be significantly lower , and theyve lost an average of about 11 pounds