The NADPH generated during this step is a potent reducing agent, serving as a critical factor in various cellular redox reactions
In order to monitor the intracellular translocation of agonists, as well as GLP-1Rs, we used fluorescently labeled exendin-4, exendin-phe1, and exendin-asp3 conjugates, with fluorescein isothiocyanate (FITC) at position K12, which we previously found useful for labeling GLP-1R 28
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All references to biological systems are provided for research context only and do not imply therapeutic use
Mar 2023;9(1)doi:10.1136/rmdopen-2022-002741
86 Gene Ontology Consortium, S