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However, like all medications, GLP-1 therapies come with potential side effects, such as gastrointestinal discomfort and risk for pancreatitis, necessitating careful medical supervision

However, Eggers test detected a significant risk of publication bias in MCI brain GSH literature (bias [95%CI] = 11.28 [20.6, 1.95], p =0.03) and AD blood GSH literature (bias [95%CI] = 5.18 [9.96, 0.40], p =0.035)

Common gastrointestinal side effects occur in many patients and include: Nausea (most common, typically improving after 4-8 weeks) Vomiting Diarrhea Constipation Abdominal pain or discomfort Decreased appetite These effects result from the drugs' mechanism of actionslowing gastric emptying and affecting gut motilityrather than indicating tissue damage or malignancy

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