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As IGF-1R mAbs are readily available for human use, these observations warrant further study into potentially harnessing these drugs to target at least some manifestations of aging
Mutagenesis (2004) 19(4):32530
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For example, the roles of genetic predisposition, age, and comorbidities in modulating susceptibility to neurotoxicity remain underexplored
Recent observations highlighted the critical association with intestinal flora, as confirmed by the finding that metformin decreased the relative abundance of Bacteroides fragilis while increasing Akkermansia muciniphila and Bifidobacterium bifidum
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