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The glutathione peroxidase pathway is further regulated by System Xc-, an amino acid antiporter consisting of a disulfide-linked heterodimer of xCT/SLC7A11 and SLC3A2/4F2hc/CD98, and is inhibited by the ferroptosis inducer erastin (4)

Next, we used the pro-inflammatory cytokines tumor necrosis factor- (TNF-) and interleukin-6 (IL-6) as indicators to evaluate the anti-inflammatory response

When considering combination with conventional pharmacological agents, BPC-157's influence on the nitric oxide system and vascular function warrants attention to potential interactions with cardiovascular medications, particularly those affecting blood pressure or vascular tone

ChemMedChem 13 , 21892201 (2018)