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People with gastrointestinal or autoimmune conditions: Diseases like Crohn's, celiac, or pernicious anemia can block B12 absorption
Nayana Shetty, MBBS, MD When to See a Doctor Although rare, some people may experience side effects of high vitamin B12 levels such as headaches or skin reactions
Although cyanocobalamin is more readily absorbed, much of it is excreted through the urine before it can reach the cells Cyanocobalamin vs Hydroxocobalamin In comparison to hydroxocobalamin, cyanocobalamin has a significantly worse absorption rate and storability, which is why today mostly hydroxocobalamin is used in B12 injections
Do note, pernicious anemia rarely visits alone
However, breastfeeding and pregnant women need about 2.8 mcg and 2.6 mcg, respectively
