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Notably, administering the PPT1 inhibitor hexadecylsulfonylfluoride (HDSF) to both healthy volunteers and SLE patients reduces IFN production ex vivo, underscoring its therapeutic potential for autoimmune diseases
In addition, GLP-1RAs inhibit superoxide anion formation and ensuing VSMC senescence through suppressing Rac1 activation via cAMP/PKA pathways [123]
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The peptide diffuses into the damaged area where it stimulates collagen synthesis and attracts healing cells
It does this by reducing the damage caused by oxidative stress, which is caused by free radicals