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Another major safety concern involves dosing errors, especially with compounded medications
The high OCTN2 expression is associated with poor overall patient survival and a siRNA-mediated OCTN2 silencing in GBM led to a loss of tumor cell viability (Wang et al., 2012)
Full results aren't available yet, but Novo Nordisk said there was a "statistically significant" 0.83% reduction in A1c levels with semaglutide compared to placebo at that time point
Semaglutide is a peptide that must be injected once a week
This latest approval for Wegovy simply allows doctors to formally expand treatment to a larger group of people: those with overweight or obesity who have cardiovascular disease but not diabetes
It allows Novo to defend its semaglutide franchise while broadening access to patients who prefer oral therapy
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