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Not only did different animal models such as rats, mice, rabbits and hamsters, help in the discovery and understanding of the therapeutic pathway of GLP-1 drugs, but they also provided crucial data on drug safety, pharmacokinetics and organ-specific effects, all of which were necessary for achieving regulatory approval and the successful translation to human use

Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits: a comparison with bone marrow and autologous cortical bone implantation

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Normally, ghrelin binds to them and sends a signal from the hypothalamus to the pituitary gland that stimulates the release of human growth hormone (hGH)

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