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A double-blind RCT (n=33) evaluating the effects of oral coenzyme Q10 on the skin found improvements in wrinkles and skin smoothness, but no changes in skin hydration, dermal thickness, or minimal erythema dose.46 Another double-blind RCT (n=34) found that a dietary supplement containing coenzyme Q10, oral collagen, vitamin C, vitamin A, and biotin for 12 weeks reduced facial wrinkles and increased dermal density, but had no impact on skin hydration or thickness.47 Oral Glucosamine Oral glucosamine sulfate is widely used in osteoarthritis
doi: 10.1515/JPEM.2010.23.1-2.101 31 YazbeckRHowarthGSAbbottCA
Drug shortages during the study period may have caused some temporary discontinuations that looked like intentional stops
Lung Although the lung is not generally regarded as the main site of lipid metabolism, carnitine metabolism has also been increasingly implicated in respiratory diseases [300]
Korner does applaud having more options for patients in a group of medicines that's proven to be beneficial beyond weight loss
