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Basic and therapeutic aspects of angiogenesis
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Impaired activity of methionine synthase results in elevated blood concentrations of homocysteine, while impaired activity of L-methylmalonyl-CoA mutase results in increased concentrations of a metabolite of methylmalonyl-CoA called methylmalonic acid (MMA) in blood and urine
Hrehorck M et al
Tirzepatide mimics GLP-1 and another hormone with similar effects called gastric inhibitory polypeptide (GIP)
Overall, investigators found that 63 percent of participants had a reduction in steatohepatitis (inflammation of the liver with fat accumulation in the liver) versus 34 percent for the placebo group
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