Over-dosing or skipping titration steps can cause severe nausea, dehydration, gastroparesis (delayed stomach emptying), and in rare cases pancreatitis or hypoglycemic events
Research has demonstrated involvement of the NO system, growth factor modulation (including VEGF, EGF), and FAK-paxillin signaling pathways
During a flare, gentle foods often feel safer
Inflammatory bowel syndrome, intestinal lymphomas, vomiting or diarrhea are reported to cause problems in cobalamin absorption
Cyanocobalamin injections are mostly given once a month once your B12 deficiency anemia has been treated to prevent a recurrence of symptoms that could lead to nerve damage
While human clinical data is limited, years of anecdotal use and animal studies have helped shape reliable dosing practices