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Clinical trials of GLP-1 medications show that up to about 40% of weight loss can come from lean mass, highlighting the importance of protein intake, resistance training, and overall nutrition support to help preserve muscle during weight loss

GLP-1 receptor agonists and risk of cancer in type 2 diabetes: An updated meta-analysis of randomized controlled trials

Brains were later sectioned on Leica CM3000 cryostat, and 1 mm punches (Integra Miltex Biopsy Punch) of the hypothalamus, hippocampus and hindbrain were collected

Whether HbA1c moves meaningfully in humans and at what dose, route, and duration is untested

So because of that, I try to avoid surgery, using medications for weight loss

Glucose metabolism modulation Studies suggest it may inhibit gluconeogenesis (glucose production in the liver) and enhance glycolysis (glucose breakdown), thereby potentially reducing blood glucose levels