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12.2 Pharmacodynamics The pharmacodynamic evaluations described below were in patients with type 2 diabetes mellitus who received once weekly subcutaneous injections of placebo or semaglutide injection over 12 weeks (semaglutide injection-treated patients were started on lower dosages and then titrated up to 1 mg once weekly)
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In July, to mitigate these challenges, Novo Nordisk issued a directive to health professionals in the UK to only prescribe semaglutide to those patients who are eligible for it, and to be restrained with new prescriptions, to prevent those who genuinely relied on the drugs for their health from being unable to acquire it
Additionally, monitoring for signs of mood changes, gastrointestinal distress, and other potential side effects is crucial to ensure patient safety and treatment efficacy
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