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MRI of the brain characteristically reveals centric necrosis of the caudate nucleus head bilaterally and partial or complete necrosis of the shell nucleus in individuals with BTBGD

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It also modulates serotonin, dopamine, and norepinephrine in limbic circuits (Zozulia et al., Zh Nevrol Psikhiatr Im SS Korsakova 2008)

The result is eyelid flickers, facial twitches, or random pulses that seem to come out of nowhere