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Those with certain health conditions may also need extra monitoring
A 2025 systematic review of the compound identified only 36 total studies, 35 of which were conducted on animals and just one single study (with a sample size of 12!) conducted on humans
Some dermatologists dismiss it entirely, arguing copper peptides at standard concentrations can't cause significant damage
As with any potent active, sideeffect potential exists (especially with retinoid: irritation, sun sensitivity)
Vitamin B12 deficiency has occurred in breastfed infants of vegetarian mothers whose diets contain no animal products (e.g., eggs, dairy), even though the mothers had no symptoms of deficiency at the time
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