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Activating both receptors can improve insulin secretion, enhance fat metabolism and amplify appetite suppression

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Cagrilintide solves this through lipidation technology that extends its half-life to 159 to 195 hours, allowing once-weekly dosing instead of multiple daily injections

A double-blinded placebo-controlled phase 2 clinical study in obese patients weekly injections of mazdutide (9 mg) could cause 15.4% decreases in body weight over placebo after 24 weeks

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