While federal law allows the prescription of compounded drugs, they are not FDA-approved and do not undergo safety, effectiveness, or manufacturing review by the FDA
How it works: When liver glycogen is depleted, fatty acids are metabolised to acetyl-CoA, then converted to ketone bodies (acetoacetate, -hydroxybutyrate, acetone)
So maybe the drug needs to be used in combination with a sensible diet and exercise regime, if the weight is to stay off
Tirzepatide, a dual glucagon-like peptide-1 (GIP) and GLP-1RAs, administered once weekly at a 15 mg dose, resulted in an average weight loss of 20.9% over 72 weeks (Jastreboff et al., 2022), driven by its synergistic effects on appetite regulation, energy intake reduction, and fat mass decrease (Heise et al., 2023)
A SHIFT IN THE FITNESS WORLD
A 2014 study in the Journal of Neuroscience found that activating spinal GLP-1 receptors specifically suppressed pain hypersensitivity via spinal microglia [7]