fda glp-1 compounding crackdown news today New project announcement: HHS‑OIG is taking a closer look at FDA's oversight of compounded GLP‑1 drugs. Although shortages ended in 2025, some facilities may still be producing these drugs at scale. Our Compounded GLP-1s Become Illegal, Price

[cited 2025 Mar 20]

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The two manufacturers of approved GLP-1s, Lilly and Novo Nordisk, have set up online platforms to bypass both compounding and traditional pharmacies, and Lilly has partnered with three telehealth services to provide access to obesity-trained doctors and registered dietitians

Compared to the placebo (-4.0), liraglutide resulted in a greater change in BMI as a percentage of the 95th percentile (-14.0), and an estimated treatment difference of 10.0 (95% CI, 15.1 to 4.8) was observed

For someone starting at 180 pounds, that may look more like 18 to 27 pounds

255,256 Replacing the phosphate backbone by other group improves target affinity, nuclease resistance, and pharmacokinetic properties of nucleic acids