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The consequences are albuminuria and progressive kidney failure, resulting in complete glomerulosclerosis and kidney failure at around 37 weeks of age

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Strategic manipulation of intrinsic pathways, exemplified by Phosphatase and Tensin homolog (PTEN) inhibition, can suppress growth constraints and re-activate robust axonal extension [267, 268]

doi: 10.1002/cphy.c140003 12 WangCCatlinDHStarcevicBLeungADiStefanoELucasGet al

The sections were incubated with a 1: 50 dilution of FITC-labeled anti-mouse IgG (Santa Cruz, USA), and the nuclei were stained with propidium iodide (PI) at 37C for 15 min