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There are no contraindications or warnings against combining influenza vaccination with semaglutide therapy in the FDA-approved prescribing information for Ozempic, Wegovy, or Rybelsus

Clinical studies suggest that GLP 1 & GIP therapy may be even more effective than GLP 1 alone, with patients often experiencing greater weight loss in a shorter period

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10.1084/jem.20181776 6 AmbrozewiczE.WojcikP.WronskiA.LuczajW.JastrzabA.ZarkovicN.et al (2018)

This [study] suggests that here are potentially alternative mechanisms for that improved cardiovascular outcome with semaglutide beyond weight loss Quite clearly, something else is going on that benefits the cardiovascular system, Deanfield said