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The data is clear on this

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Some of the key responses that are triggered include: Increased insulin Trusted Source Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial Kapitza C, Dahl K, Jacobsen JB, Axelsen MB, Flint A Go to Source secretion, so that glucose from food gets burned for energy instead of stored as fat Slowed gastric emptying Increased satiety Reduces cravings for sweet and fatty foods Weight loss Together, these biological responses contribute to the effectiveness of GLP-1 in promoting weight loss and improving blood sugar regulation in individuals with type 2 diabetes or those with obesity

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Our data also shows that patients experiencing gastrointestinal side effects on semaglutide will be less likely to experience them on tirzepatide