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Because its research-grade (rather than consumer-approved) and considering its ability to cross the blood brain barrier, the key is: start modestly, track your response, and adjust only when justified

"This blocks interactions between melanocytes [the skin cells that produce melanin] and keratinocytes [cells that provide skin structure]." By blocking interactions between the two, dark spots, signs of melasma, and post-acne hyperpigmentation become less pigmentated, creating a clearer, more radiant tone

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What is known comes from small studies, case reports, and user-reported side effects