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[16] [2] It is important to check and replace folate after starting B12 therapy, as coexisting deficiencies are common and correcting B12 alone can precipitate or worsen folate deficiency

Of these 36 studies, 35 were preclinical animal experiments

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The symptoms of vitamin B12 deficiency can be quite debilitating and include, according to scientific research: Chronic fatigue and weakness Shortness of breath Heart palpitations Tingling or numbness in the extremities Poor balance Loss of concentration and poor memory Disorientation Mood changes, including depression Insomnia Imagine trying to maintain a healthy, active lifestyle when you're constantly battling severe fatigue and low energy

Brcic et al

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