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33 In this study, we hypothesized that Klotho deficiency plays an important role in cardiac aging and that supplement with exogenous secreted Klotho protects against cardiac remodeling and heart failure in Klotho-deficient and aged mice

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There is no evidence that GLP-1 receptor agonists alter neuromuscular junction function or affect how botulinum toxin binds to its target sites, though it should be noted that direct clinical studies specifically examining concurrent use are limited

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