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This action leads to closure of glucose-dependent ATP-sensitive K + channels which depolarizes the cell and thereby opens voltage dependent Ca 2+ channels allowing Ca 2+ influx which stimulates insulin secretion

Publisher | Google Scholor Wong CK, Yusta B, Koehler JA, Baggio LL, McLean BA, et al

Patients often report not only weight loss but also improvements in energy, motivation, and their relationship with food