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A combination of interrelated effectors such as glutamate excitotoxicity, mitochondria dysfunction, glial cell pathology, impaired axonal transport, protein aggregations, and neurotrophic factor deficits leads to progressive motor neuron degeneration and eventual death
(3) Mokhtari, V., Afsharian, P., Shahhoseini, M., Kalantar, S
These results are consistent with those presented by Kaur and Bansal [37]
In addition, we discuss the increase in the endogenous secretion of this hormone through various stimuli (e.g., carbohydrates, proteins, gut microbiota, bacteria-derived molecules, bile acids, lipids, fatty acids, polyphenols, etc.) or by the increase of GLP-1-producing cells, i.e., L-cells, which can be an appropriate approach for the management of diabetes
[PMID: 7181116] PubMed record related to this compound for laboratory literature review
This balance of efficacy and tolerance represents the optimization goal
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