The selective action of AOD-9604 on fat tissue, without growth hormone receptor activation, eliminates these concerning safety issues
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5-Amino-1MQ inhibits the enzyme NNMT (nicotinamide N-methyltransferase), which preserves intracellular NAD+ and activates AMPK-dependent mitochondrial fat oxidation
In addition, combination of NNMTi with exercise further increases systemic energy expenditure, accelerates fat breakdown, and enhances muscle strength and endurance
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