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There was mild local interface inflammation and small bile duct injury

This is in line with studies showing that GLP-1 increases vascular blood flow and activates glucose delivery into skeletal muscle via AMP-activated protein kinase (AMPK), thereby promoting muscle synthesis, reducing muscle breakdown (50, 51) and improving muscle microvascular recruitment (MVR) through increased endothelial surface area (52)

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Additionally, Mohiuddin et al (165) indicated that GLP-1RAs exerted neuroprotective effects through direct action on root ganglion neurons

Cells overexpressing HMGA2 significantly inhibit ferroptosis by suppressing ROS and promoting the production of GSH