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In the Phase 2 clinical trial published in The New England Journal of Medicine in 2023, gastrointestinal side effects affected the majority of participants, with nausea, vomiting, diarrhea, and constipation being the most frequent complaints

Unlike prescription medications, dietary supplements are not required to undergo rigorous clinical trials to prove their efficacy or safety, says Dr

Some individuals experience reflux during dose escalation phases, while others notice symptoms level off as their bodies adapt over 4-8 weeks

Sandhu, M

Islet alpha cells and glucagoncritical regulators of energy homeostasis

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