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Repurposing anti-diabetic drugs for the treatment of Parkinson's disease: Rationale and clinical experience
The increased dipeptidyl peptidase-4 activity is not counteracted by optimized glucose control in type 2 diabetes, but is lower in metformin-treated patients
As neurotransmitters play a critical role in the function of the central nervous system, the disrupted metabolism of monoamine neurotransmitters can increase the risk of depressive behaviors
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In another paclitaxel-induced peripheral neuropathy (PIPN), 4-PSQ was observed to decrease paclitaxel-induced mechanical and thermal hypersensitivity, possibly related to modulation of oxidative stress in the spinal cord, hippocampus, and cerebral cortex of PIPN mice [163]
By weeks six to eight, energy levels and recovery from exercise show measurable changes
