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The first dose is 1000 mcg of vitamin B12 given IM every day for a week
Cheryl Bugailiskis, M.D
How to Administer TB-500 Nasal Spray To administer TB-500 nasal spray to subjects in a research setting, adhere to the following procedure: Prepare the nasal spray: Ensure that the TB-500 nasal spray is properly prepared according to the recommended concentration and formulation guidelines
Handling: Store the lyophilized vial refrigerated at 28C, protected from light and heat
In such cases, the NHS standard treatment is intramuscular hydroxocobalamin injections, typically given every 2-3 months for maintenance after an initial loading regimen
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