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Now that popularity of the drugs has exploded, Scanlons office needs to find new ways to control costs

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The absence of leg cramps from official labeling does not definitively rule out a connection, as post-marketing experience sometimes reveals adverse effects not detected in pre-approval trials due to sample size limitations, duration of follow-up, or patient population differences

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hence, the efficacy of Lixisenatide compared to the placebo might have been lessened

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