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Studies performed after the last clinical trial, in induced pluripotent stem cells (iPSCs) derived from patients with ALS (Yang et al., 2013), in rat primary cortical neurons transfected with human mutant TDP-43 as well as in the SOD1 G93A mouse model (Vieira et al., 2014) showed no beneficial effect
However, the study grouped dosages of under 50 mg together, making it hard to determine the risk of low dosages of iron, such as those in many multivitamins
Lightening of Hori's Nevus is present but not drastic
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