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While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

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Funding was provided by the Medical University of Biaystok, Poland (Grant No.: B.SUB.25.250)

In other words, glutathione is directly applied to the skin in the form of cream and absorbed locally