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Glucagon-like peptide-1 receptor agonists (GLP-1 RA) and dipeptidyl peptidase 4 inhibitors (DPP-4i) were both introduced in Denmark in 2007, and new drugs in the classes are continually being introduced (5)
EXAMPLE 2 preparation of Merrifield Resin and 1- (3-hydroxypropyl) -1H-imidazole solid phase support Referring to the synthesis method of example 1, 1- (3-hydroxypropyl) -1H-imidazole reacts with Merrifield Resin to prepare Merrifield Resin with 1- (3-hydroxypropyl) -1H-imidazole ionic liquid as Linker, and the specific structure is as follows: EXAMPLE 3 preparation of Fmoc-Gly-1- (2-hydroxyethyl) imidazole hexafluorophosphate-Merrifield Resin Weighing 20 g of 1- (2-hydroxyethyl) imidazole hexafluorophosphate-Merrifield Resin prepared in example 1 into a solid phase reaction column, adding DMF, and carrying out bubbling swelling for 60 minutes by nitrogen
Lancet 403 (10431), 10271050
Vilsbll T, Bain SC, Leiter LA, et al
big molecule from repeated subunits) that is used to stabilize emulsions as well as to thicken up products
Insulin inhibits glucagon secretion by the activation of PI3-kinase in In-R1-G9 cells
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