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A 2018 review article published in the Journal of Clinical and Aesthetic Dermatology found that glutathione may be an effective treatment for hyperpigmentation and skin whitening

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On the contrary, the use of small molecules derived from diet that alter the levels of ROS, such as diallyl disulfide, polyphenols, isothiocyanates, and terpenoids has been suggested for the treatment of cancer by promoting ROS generation and GSH depletion in cancer cells (Filomeni et al., 2003

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