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Artemisinin activation is decreased in PfK13 mutant lines Artemisinin requires activation by free heme, thus we anticipated that the decrease in heme levels observed in 3-6 hpi ring-stage parasites would result in decreased artemisinin activation and, therefore, decreased activity
International Journal of Oncology
General Chapter 797, Pharmaceutical Compounding, Sterile Preparations
It's not just treating the surface symptoms
Zoughaib WS, Hoffman RL, Yates BA, Moorthi RN, Lim K, Coggan AR
Larabi, for their help with protein expression, purification, crystallization and X-ray diffraction analyses
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