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The mechanism by which it is regulated and potentially inhibited promises novel avenues for treatment of aggressive types of malignancies 15,16,17,18,19

Adding both GSSG and DsbA at the same time did not even double the probes oxidation rate, indicating an additive effect of GSSG and DsbA and not a GSSG-driven catalytic action of DsbA

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The results were confirmed for the non-related enzyme PfGrx with its homologous residues Lys26 and Asp90

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